10 reasons you should purchase Penegra

Erectile dysfunction (ED) is also known as as male impotence or simply impotence. It is a type of sexual disorder in men in which a man is persistently not able to get or maintain firm and strong erection of penis for extended period of time for satisfactory sexual intercourse. It majorly affects the men above 40 years of age. But nowadays even young men above 20 years are affected in large numbers.

The cause of ED can be physical or psychological. Physical causes include diabetes, obesity, surgery, injuries to the penis, blood pressure lowering medicines, medicines used in treatment of depression, addictions such as smoking and alcohol consumption, poor lifestyle. Psychological causes include stress, depression, anxiety and frustration.

Erectile dysfunction can be treated with medicines, making lifestyle changes, use of penile pumps, penile implants, and herbs or other natural remedies and surgery. Surgery is considered as the last option when all above methods of treatment do not work out.

The most widely used treatment for ED is with phosphodiesterase type 5 inhibitors (PDE-5 inhibitors) as it is the most convenient a method of treating ED and produces faster results and does not involve any recovery period.
Penegra and its active component

Penegra is generic equivalent of brand Viagra. It contains Sildenafil Citrate as the active pharmaceutical constituent, which was the first effective drug approved by the Food and Drug Administration (FDA) in the year 1998 for treating ED. This is a prescription based drug and so is only sold on prescription. Sildenafil citrate is a potent PDE-5 inhibitor. Penegra are sold as 100mg oral tablets.

Mechanism of Action

Penegra increases the concentration of the enzyme cGMP inside the penile region by preventing its degradation by PDE-5 enzyme. The function of cGMP inside the penis is relaxation of smooth muscles and dilation of the blood vessels inside the penis. The dilated blood vessels increase the amount of blood flowing into the penis which results in a firm and strong erection of the penis for penetration into the female vagina which gives complete sexual satisfaction and complete sexual pleasure.

1. 10 Reasons you should purchase Penegra
2. You only need to take a single 100mg oral tablet once in a day
3. This medicine is to be taken with a glass of water about 30 to 60 minutes before sexual activity; so it very easy to
4. The effect of this medicine starts within 30 to 120 minutes hours after oral administration.
5. The effect of this medicine lasts for an average duration of 4 hours.
6. It is available at lower price than its branded version Viagra
7. If you purchase Penegra Tablets online pharmacies like MedexpressRx, you can get them at still lower prices than local pharmacies.
8. Also, they are available at exciting offers and impressive discounts at online pharmacies
9. You also receive free shipment of online ordered medicines above orders of $100 and $250.
10. You get more discount than the other customers if you are the regular customer of online pharmacy of MedexpressRx.
    
    Penegra can be taken with or without food as it does not show any interaction with food.

A Word of Caution

• Do not drive or operate machinery after taking this medicine.
• Take the missed dose as soon as you remember.
• Skip the missed dose if it’s time to take next scheduled dose.
• Do not consume an extra dose in order to compensate for a missed dose.
• Call your doctor if an overdose is suspected.
• Use of this medicine in pregnant women, nursing mothers and men below 18 years of age is not suitable

Common Side effects

• Headache
• Pain in back and muscles
• Vision changes
• Diarrhea
• Flushing
• Nasal Congestion

The Advantages of Using Sildenafil Citrate 100mg

Erectile dysfunction is a disorder where men r not able to maintain a firm and stable erection for sexual intercourse on a regular basis. This disorder is responsible for creating a havoc in the sexual life of men as well as his partners. Causes of this disorder are multifactorial and the multi factorial and the progression of the disease does not depend on the single factor. Numerous treatment strategies are developed for the management of this sexual dysfunction disorder.


These include Lifestyle modification, medications, penile implants, cognitive behavioral therapy, surgeries, herbal medications etc. The causes of erectile dysfunction are bifurcated majorly into organic and psychogenic. Organic disorders include heart diseases, diabetes neurological conditions like multiple sclerosis, stroke etc.

Metabolic conditions like Diabetes mellitus type 1 and type 2 are considered by many Healthcare Experts as an independent risk factor for the occurrence of long term or permanent erectile dysfunction.

Out of the above mentioned treatment approaches, medications which inhibit the enzyme phosphodiesterase 5 are the main line therapy for the treatment of erectile dysfunction. Sildenafil citrate which is popular by the name of generic Viagra is the gold standard of treatment of male impotence since its approval bike the Food and Drug Administration (FDA) in 1998. Generic Viagra is the generic version of the brand Viagra which comprises of sildenafil citrate as an active Pharmaceutical ingredient.


Sildenafil citrate present in generic Viagra selectively inhibits the cGMP dependent phosphodiesterase 5 enzyme. This increases the concentration of vasodilator biochemicals namely nitric oxide and cyclic GMP. It also promotes the release of guanylyl cyclase which in turn enhances the production of cyclic GMP. This cyclic GMP dilates the blood vessels that supply blood to the penis. This action in turn enhances the flow of blood to the male reproductive organ and prolongs the duration of the hard and firm erection.

One must remember that which medicine sildenafil citrate present in generic Viagra only in the presence of thorough sexual stimulation. Sildenafil Citrate 100 mg medicine is not to be taken along with medicines that treat hypertension like Alpha blockers and medicines that treat angina like nitrates. Concomitant use Mike cause a drop in blood pressure and fainting.

Also one must remember that this medication is a prescription this medication and should be taken after consulting registered medical practitioner. Side Effects include prolonged erection upto 4 hours which is called as Priapism, dizziness, nausea and vomitting, visual disturbances, nasal congestion, irregular heartbeats etc. It should be noted that this medication is not to be used in adolescents, children, women and men who do not suffer from erectile dysfunction. Do not overdose on this medicine.

Also remember that this medication is to be used on as needed basis and regular use might lead to psychological dependence and habituation. Commonly available dose of this medication is 100 mg and is to be taken once daily along with a glass of water without chewing crushing or breaking. If a patient take any other medication during the therapy of generic Viagra, it should be informed to the doctor before initiation of the therapy.

Difference between Cialis and Viagra

Both Cialis and Viagra are the branded medicines prescribed for treating Erectile Dysfunction (ED). Erectile Dysfunction is a type of sexual dysfunction in men in which a man is not able to obtain or maintain an erection for extended period of time.

The outcome is unsatisfactory sexual intercourse and lack of sexual pleasure. Men over 40 years of age are commonly affected by ED. But today even a lot of young men suffer from ED. The cause of developing ED can be physical or psychological. The treatment is given according to the cause of ED. Treatment with medicines is the commonest and easiest way to treat erectile dysfunction. 

Both Cialis and Viagra belong to class of PDE-5 inhibitors. These medicines have same mechanism of action, side effects, contraindications, they have same set of warnings and same precautions are to be taken while consuming Cialis and Viagra.

Both are extensively prescribed PDE-5 inhibitors

Viagra and Cialis differ in active ingredient, FDA approval, dose, onset of action, duration of action, and interaction with food. All PDE-5 inhibitors have almost same efficacy.

Cialis

Cialis consists of Tadalafil as the active ingredient. It is the third most accepted drug after sildenafil citrate (Viagra) and Vardenafil (Levitra) for treatment of erectile dysfunction. It was approved for use in treatment of erectile dysfunction by FDA on 21^st November 2003. The widely prescribed dose is 20mg. The highest amount of dose which can be consumed in a day is 40mg.

The action of this medicine is observed within 30-60 minutes after oral administration and it persists for a period of about 36-40 hours. It exhibits an efficacy of about 81%.Its efficacy is not reduced in presence of food. So, Cialis can be taken along with food or without food. Its distinguishing characteristic is its long half-life of 17.5 hours.

Thus, most of the men prefer taking Cialis than other PDE-5 inhibitors due its longer half-life. Approximately 61% of the dose is eliminated through feces and 36% is eliminated through urine. Its generic version named Generic Cialis is also available these days.

Viagra

It consists Sildenafil citrate as the active component. Sildenafil citrate was the first effective and safe drug accepted for the use in treatment of erectile dysfunction. It was accepted for use in erectile dysfunction by FDA on 27^th March 1998.

Within a period six months of its approval, millions of prescriptions were written for Generic Sildenafil Citrate. The discovery of Viagra was breakthrough discovery in the field of sexual medicine. The widely prescribed dose is 100mg once a day in most cases. A maximum dose of 200 mg can be consumed in a day.

The effect of this medicine is observed within 30-120 minutes after taking the medicine. The action persists for an average duration of 4 hours. The absorption of this medicines is decreases by 50% in presence of food rich in fat content.

This medicine exhibits efficacy of 84%.  Approximately 80% of the administered dose is eliminated through feces and approximately 13% of the administered dose is eliminated through urine. Its generic version named Generic Viagra is also available these days.

5 Healthiest Green Leafy Vegetables

Leafy green vegetables are an imperative part of a fit diet. They’re filled with vitamins, minerals and fiber but little in calories. Eating a diet rich in leafy greens can offer many health aids with abridged risk of obesity, heart disease, high blood pressure and mental weakening. Five of the healthiest leafy green vegetables to include in your diet are as follows:

1. Kale

One of the most nutrient-dense vegetables on the planet is Kale as it has many vitamins, minerals and antioxidants. Antioxidants like lutein, carotenoids and beta-carotene, which prevent oxidative stress are found in abundance in kale. To get maximum nutrients out of Kale, It is to be eaten raw since cooking can reduce its nutrient profile. Kale is rich in minerals, antioxidants and vitamins, chiefly vitamins A, C and K.

2. Microgreens

Microgreens are undeveloped greens produced from the seeds of vegetables and herbs. They characteristically measure 1–3 inches. Despite their small size, they’re full of color, flavor and nutrients. In fact, one study found that microgreens contain up to 40 times more nutrients compared to their mature counterparts. Some of these nutrients include vitamins C, E and K. Microgreens can be grown at your home all year round, making them easily available. Microgreens are immature green which have been popular as they are packed with nutrients like vitamins C, E and K. They can be grown annually all year round.

3. Broccoli

Broccoli fits to the cabbage family with a large flower head and a stem, making it similar in structure to cauliflower. Rich in nutrients, a single cup (91 grams) of raw broccoli packing 135% and 116% of the DVs for vitamins C and K, respectively. It’s also a great source of fiber, calcium, folate and phosphorus. Broccoli is richest in the plant compound sulforaphane, which may improve your bacterial gut flora and decrease your risk of cancer and heart disease. Sulforaphane may even reduce symptoms of autism. One randomized double-blind study in 26 young people with autism revealed positive effect on behavioral symptoms after intake of sulforaphane supplements from broccoli sprouts.

4. Collard Greens

They’re similar in texture to kale and cabbage. In fact, their name comes from the word “colewort,” meaning “the wild cabbage plant.” Collard greens are a good source of calcium and the vitamins A, B9 (folate) and C.  Collard greens have thick leaves and are bitter in taste. They’re one of the best sources of vitamin K, may reduce blood clots and promote healthy bones.

5. Spinach

Spinach is a popular leafy green vegetable that can be used in a multiplicity of ways. It’s a great source of folate, which may prevent neural tube defects like spina bifida, during pregnancy.
Vitamin B, and B12 are Water soluble vitamins present in spinach